Postoperative Troponin Screening: a Cardiac Cassandra? Running title: Beckman; Troponin: Barometer or Weathervane?

Cardiac enzyme in emergency medicine

Objective: Acute chest pain is an important and frequently occurring symptom in patients. Chest pain is often a sign of ischemic heart disease. Chest pain due to suspected Acute Coronary Syndrome (ACS) is responsible for a large and ijncreasing number of hospital attendances and admissions. Current practice for suspected ACS involves troponin testing 10–12 hours after symptom o...

Multiple Reaction Monitoring to Identify Site-Specific Troponin I Phosphorylated Residues in the Failing Human Heart Running title: Zhang et al., Targeted quantitation of cardiac troponin I phosphorylation

Concordance, variance, and outliers in 4 contemporary cardiac troponin assays: implications for harmonization.

BACKGROUND Data to standardize and harmonize the differences between cardiac troponin assays are needed to support their universal status in diagnosis of myocardial infarction. We characterized the variation between methods, the comparability of the 99th-percentile cutoff thresholds, and the occurrence of outliers in 4 cardiac troponin assays. METHODS Cardiac troponin was measured in duplicat...

Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population.

BACKGROUND Between-assay comparability of 99th percentiles for cardiac troponin concentrations has not been assessed systematically in a single population for a large number of assays. METHODS We determined 99th percentiles for 19 cardiac troponin assays in heparin plasma samples from a population of 272 and 252 presumably healthy males and females, respectively. The assays evaluated included...

Electrocardiograph changes, troponin levels and cardiac complications after orthopaedic surgery.

INTRODUCTION The relationship between electrocardiograph (ECG) changes and troponin levels after the emergency orthopaedic surgery are not well characterised. The aim of this study was to determine the correlation between ECG changes (ischaemia or arrhythmia), troponin elevations perioperatively and cardiac complications. MATERIALS AND METHODS One hundred and eighty-seven orthopaedic patients...